The 2016 model year brought the arrival of an all-new, fourth-generation Lexus RX 350 to market, along with its siblings. These included an extended-wheelbase RX-L configuration, an athletic F-Sport model variant, and both gas and hybrid-powered units.This latest RX represented a major advancement on the previous third-generation machine, which ran from 2010 to 2015 model years inclusive. Advancements abounded, and the latest generation of Lexus' hot-selling SUV earned rapid recognition for its celebrated interior.Today, 10 years on, that all-new cabin stands up well and represents some tremendous value for used shoppers, provided they bear a few important details in mind. We'll delve into those below.In 2016, Lexus was making a lot of headlines. This would be their fourth consecutive year of record global sales, and many of those sales came from SUVs. Of said SUVs, the RX was one of the brand's longest-running nameplates, having arrived originally in 1998. This machine was, by this point, an authority in the SUV scene. What Makes Its Interior So Special? LexusLexus sought to help its freshly updated bestseller stand out by way of an interior that quickly earned a reputation as one of its most valuable assets. By this point, Lexus was well-known for making some of the best luxury interiors in the game. Even drivers who didn't care for the actual styling and colors of the brand's interiors had to admit that the execution and tactile response from every control conveyed a crafted and overbuilt feel.Building on a long-held knack for excellent interior quality and design, the interior in the new-for-2016 Lexus RX was definitely not messing around. The latest design language gave drivers a modernized take on the signature Lexus cockpit: formal, inviting, and overflowing with attention to detail. In this way, the latest new-for-2016 RX's cabin was as top-notch as owners expected.Lexus The latest cabin was also bigger and more accommodating, with seats and steering wheel repositioned carefully to ease entry and exit. Though designers kept the RX's overall size about the same as its predecessor at the request of customers, the latest RX's structural advances freed up additional space throughout.Lexus Controls from the window switches to the signal stalk to the gearshift lever all felt solid, heavy, and overbuilt. Excellent control over squeaks, rattles, and vibrations delivered flagship-level refinement without the price. Right down to the power window motors, door handles, and operation of the sunroof and tailgate, every driver command in an RX is met with a pleasing response that conveys the quality feel expected.Craftsmanship and attention to detail rewarded eyes and fingertips of occupants at every turn, and test-driving shoppers eyeing up a big spend had no trouble feeling like they were getting their money's worth in the cabin of a modern Lexus.Building on all of this, the latest RX now flaunted some spicy color options for drivers after a more dynamic experience, perhaps via the agile F-Sport model. Interior trims included Matte Bamboo, Espresso Walnut, Matte Linear Dark Mocha Wood, Striated Black Trim, or Gray Sapele Wood with Aluminum. A Striated Black Trim brought a glossy black base with an embossed 3D pattern applied to create a sense of luxurious depth. Selected Luxury and Technology Features Of The Lexus RX 350 LexusTouch-Free Power Rear Door: Allowed drivers to open the tailgate by simply waving a hand or elbow near the rear emblem Active Sound Generator: Exclusive to F Sport models, this intake-mounted device uses a vibrating diaphragm to amplify natural engine frequencies, pumping a mechanical "growl" into the cabin during spirited acceleration Lexus Climate Concierge: Special sensors monitor the surface body temperature of all occupants, automatically co-ordinating the climate control system and heated/ventilated seats for individual comfort Adaptive Variable Suspension (AVS): A high-performance damper system that adjusts shock absorber damping rates up to 30 times per second to optimize drive quality in real time Power-Folding & Reclining Second Row: Aside from merely sliding, the RX 350's rear seats feature a power-folding mechanism controllable from the driver’s seat or cargo area, allowing them to flatten or return upright at the touch of a button. Panoramic View Monitor with "See-Through" View: Utilizes four high-resolution cameras to create a bird’s-eye perspective, including a unique mode that makes the car's body appear transparent on-screen to see exactly what is underneath the chassis. "Easy Exit" Seat & Steering Wheel: To maximize entry and exit space, the steering wheel automatically tilts up and away while the driver’s seat slides rearward as soon as the ignition is turned off. A few months after it went on sale, the 2016 RX earned a coveted spot on the "10 Best Interiors" list, published annually by Ward's Auto. For that win, the vehicle in question must have an all-new interior for the US market and earn top marks after evaluation on materials, ergonomics, safety, comfort, value, and fit-and-finish. Further, note that the latest RX's new body structure was considerably stiffer than the structure of its predecessor, which has direct benefits to interior comfort and noise levels.Lexus It wasn't all great news on board. This generation's initial infotainment system required drivers to use a mouse-like interface on the centre console to control on-screen functions, which was not a favorite of all drivers. This generation RX also didn't ship with must-have Apple CarPlay or Android Auto functionality until a 2020 update, which also added touchscreen functionality to help mitigate the use of the "mouse" interface. Lexus Got Serious About Turning The RX Into A Driver's SUV Lexus When the fourth-generation RX arrived, it would face increasingly turbocharged competition with a naturally aspirated base engine, offer proven hybrid power for shoppers curious about electrification, and receive a totally recalibrated driving experience intended to put it on the mental radar of driving enthusiasts for the first time.The V6 engine was bumped to 295 hp in the RX 350, and a new 8-speed automatic further sharpened response and efficiency compared to the former six-speed box it replaced. New cylinder heads were deployed to improve engine breathing, and both intake and exhaust cams were now variable. The result was a flexible and efficient performer, backed by a new AWD system that could switch from pure front-wheel drive to a 50:50 power split between the axles in milliseconds.During development of the latest RX, engineers deployed extensive efforts to energize the feel of the steering, throttle, and brakes while maintaining expected comfort levels. From the driver's seat, the latest RX was light-years ahead of its predecessor when it came to engagement, and the new AWD system with available Sport and Sport + modes made the RX 350 an athletic beast in winter driving conditions, with appropriate tires. Still A Comfortable Cruiser Despite the changes above, Lexus didn't mess around with the quality of the ride. Automakers often go too far trying to make an SUV sporty, which can ruin the experience. Unless you're in the market for a performance SUV, you likely want a sensory deprivation tank on wheels with a marshmallow-like suspension setup.The RX glides along beautifully. Even though Lexus uses words like "sporty" and some models being called F Sport, the RX is about as sporty as a mobility scooter. If you want a Rolls-Royce-like ride on a budget, the RX is the way to go. Every generation of this car has leaned hard into comfort over sportiness, and the RX is all the better for it. Still A Comfortable Cruiser Lexus Despite the changes above, Lexus didn't mess around with the quality of the ride. Automakers often go too far trying to make an SUV sporty, which can ruin the experience. Unless you're in the market for a performance SUV, you likely want a sensory deprivation tank on wheels with a marshmallow-like suspension setup.The RX glides along beautifully. Even though Lexus uses words like "sporty" and some models being called F Sport, the RX is about as sporty as a mobility scooter. If you want a Rolls-Royce-like ride on a budget, the RX is the way to go. Every generation of this car has leaned hard into comfort over sportiness, and the RX is all the better for it. Here's How Much You'll Pay In 2026 And What To Know Before You Do LexusLexus When the fourth-generation RX launched for the 2016 model year, you'd pay $42,000–$49,000 for your own copy, and about $52,000–$57,000 for a unit with hybrid power. Optional equipment and packages could add thousands more to the sticker.Today, the cheapest RX models from this generation tend to land in the $15,000 to $18,000 range, often with 150,000 miles or more on their odometers. Shop patiently, and you'll find a few examples with odometer readings closer to 100,000 miles at this price point. On the other end of the spectrum, shoppers after a low-mileage, lightly used copy of this generation RX can set a budget of about $40,000, where plenty of units with less than 15,000 miles of former use reside.Between these upper and lower limits, shoppers on a budget of about $30,000 should have little issue tracking down a copy with less than 35,000 miles on the odometer.Lexus Hybrid-powered units are available at all price points listed above, but shoppers can expect nearly double the odometer reading of a unit with a conventional gas V6. The same applies to the relatively rare RX 350 L model, which rode on an extended wheelbase for improved rear seat space.